Understanding AD SVF for Treating Knee Pain

SVF Therapy for Knee Pain

Traditional treatments like pain medications, physical therapy and joint replacement surgery have limitations, especially for younger patients.

Autologous Stromal Vascular Fraction (SVF) therapy, derived from the patient’s own fat tissue, has emerged as a promising minimally invasive treatment for knee pain. Studies have demonstrated SVF’s potential to regenerate cartilage, reduce inflammation and improve knee function.

What Is SVF, and How Does It Work?

Stromal Vascular Fraction (SVF) is a cellular mixture extracted from adipose (fat) tissue that contains mesenchymal stromal cells (MSCs), macrophages, endothelial cells, pericytes and other regenerative cell types. SVF’s therapeutic effects in knee OA are attributed to:

  • Cartilage Regeneration: MSCs can differentiate into cartilage cells (chondrocytes) to repair damaged cartilage. SVF also contains growth factors that stimulate native cartilage cells.
  • Anti-Inflammatory Action: SVF cells secrete anti-inflammatory molecules that reduce joint inflammation, a key driver of OA progression.
  • Improved Joint Environment: SVF promotes new blood vessel formation to improve the joint’s nutrient supply and remove inflammatory waste products.
Knee SVF Procedure

A: Prepare canister

B: Mark abdomen for lipoaspiration

C: Perform lipoaspiration into canister

D: Disrupt fat using ultrasonic cavitation

E: Separate aqueous solution from fat

F: Filter after centrifugation cycles

G: Inject SVF into joint in same sitting

MINIMALLY INVASIVE PROCEDURE

How Is the SVF Procedure Performed?

The SVF procedure for knee OA is minimally invasive, completed in a single surgical session of around 60-90 minutes:

  1. Fat Harvesting:
    Under local anesthesia, a small abdominal incision is made and 200-300cc of fat is gently suctioned using a thin cannula.

  2. SVF Isolation:
    The collected fat is processed using a patented ultrasonic cavitation technique to separate the SVF cellular mixture, which is then tested for dose and viability.

  3. Precision SVF Injection:
    The SVF preparation is injected precisely into the damaged regions of the knee joint using imaging guidance to ensure accurate placement.

Patients can usually start moving the joint soon after the procedure. Full recovery occurs over the following weeks.

ADVANTAGES OF AD-SVF

Benefits of SVF Therapy

  1. Natural & Safe:

    Since SVF comes from the patient’s own body, it poses no risk of rejection or major side effects, unlike donor tissue or artificial fillers.

  2. Minimally Invasive:

    The SVF procedure involves only small incisions and injections, reducing complications and recovery time versus major surgeries.

  3. Regenerative Potential:

    SVF doesn’t just reduce symptoms – it aims to regenerate cartilage and slow down joint degeneration for lasting benefit.

  4. Evidence-Based:

    A recent study found SVF significantly improved knee pain, stiffness and function scores compared to a placebo injection after 1-3 years. MRI scans also showed maintained cartilage thickness in the SVF group. No serious adverse effects occurred.

  5. Avoids Joint Replacement:

    By intervening early with regenerative SVF therapy, younger knee OA patients may be able to delay or avoid the need for an artificial knee replacement, preserving their native joint.

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Why Choose SVF Therapy for Hip AVN?

If you have been diagnosed with knee osteoarthritis and want to explore advanced SVF therapy, consult a regenerative medicine expert at KneeXpert.

Find out if you are a candidate for this cutting-edge treatment to relieve your knee pain and regain function.